Medically the evaluation by Alan Carter, Pharm.D. — composed by Jill Seladi-Schulman, Ph.D. Top top December 19, 2018

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Acetaminophen (Tylenol) and ibuprofen (Advil) room both over-the-counter (OTC) medications that have the right to be used to relieve pain.

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These medicines are 2 different species of pain relievers. Acetaminophen, sometimes noted as APAP, is its very own type, when ibuprofen is a nonsteroid anti-inflammatory medicine (NSAID).

Generally, it’s for sure to take acetaminophen and also ibuprofen together, however you’ll desire to salary close attention to how much you take it of each medication.

The key to safely taking acetaminophen and also ibuprofen is knowing how much you’re acquisition at a time and also how often.

Acetaminophen dosage

The maximum safe dosage of acetaminophen for anyone end the age of 12 is 4,000 milligrams (mg) every day. But even this quantity can injury some people’s livers, for this reason aim for no much more than 3,000 mg every day.

For kids under the period of 12, it’s best to inspect with their medical care provider to identify the safest dose for your body weight.

Keep in mental that plenty of OTC medications contain acetaminophen in a selection of doses, generally 325 mg, 500 mg, or 650 mg.

Some examples of brand-name OTC medications that may contain paracetamol include:


Remember: when looking at labels, you might likewise see acetaminophen provided as APAP.

Ibuprofen dosage

Avoid taking an ext that 1,200 mg of ibuprofen in a solitary day. OTC ib frames is often discovered in 200 mg pills. This equates to six pills a day. Still, friend should always verify just how much is in each pill.

Again, for children, it’s finest to questioning their health care provider about the safest dose for their weight.

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If you have prescription-strength ibuprofen, talk to her prescriber before mixing it with any type of other medications, including acetaminophen.


The recommended borders for adults and also children over 12 are:

3,000 mg per day that acetaminophen1,200 mg every day the ibuprofen

For children under the period of 12, contact their health care provider or refer to the product brand for dosage guidelines.

You can take ibuprofen and acetaminophen in ~ the very same time. Simply make certain to not take an ext than the recommended dose.

Some human being experience part stomach or ab pain as soon as taking the two medicines together. In this case, it’s better to alternative when you take each medication.

For example, you could take ibuprofen first, followed by acetaminophen four hours later, and also then repeat this procedure as needed.

You could likewise alternate days. Because that example, if you take ibuprofen top top Monday, take paracetamol on Tuesday and also so on.